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Roche and Dualitas enter bispecific discovery collaboration worth more than $1bn

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Roche and Dualitas Therapeutics have entered a large-scale bispecific antibody discovery collaboration potentially worth more than $1 billion across immunology and inflammation programmes.


Roche will pay Dualitas $36.5 million upfront to screen more than 300,000 bispecific antibody combinations using Dualitas' discovery platform against selected therapeutic targets.


The collaboration combines Roche's development capabilities with high-throughput bispecific screening and gives Dualitas potential milestone and commercial payments exceeding $1 billion.

Field

Content

Alert Type

Deal

Companies

Roche; Dualitas Therapeutics

Deal Type

Discovery and licensing collaboration

Asset or Company

Bispecific antibody discovery platform

Therapy Area(s)

Immunology; inflammation

Technology or Modality

Bispecific antibodies; high-throughput antibody screening

Deal Value

US$36.5 million upfront with total potential economics exceeding US$1 billion

Screening Scale

More than 300,000 bispecific combinations

Geography

Global

What Happened

Roche entered a discovery collaboration with Dualitas to identify bispecific antibody candidates for selected immunology and inflammation targets.

Why It Matters

The agreement applies high-throughput screening to a very large bispecific design space, potentially accelerating identification of differentiated therapeutic combinations.

Supporting Context

Dualitas' platform is designed to generate and screen large libraries of bispecific antibodies to identify combinations with desirable biological activity and drug properties.

Strategic Rationale

Roche gains access to a scalable bispecific discovery engine while Dualitas receives upfront funding and substantial milestone-based economics.

Potential Impact

Successful programmes could generate new biologic therapies for inflammatory and immune-mediated diseases.

Key Takeaway

Roche is paying US$36.5 million upfront in a bispecific discovery collaboration with Dualitas carrying more than US$1 billion in potential total value.

What to Watch

Selection of development candidates, advancement into preclinical studies and disclosure of specific disease targets.

Primary Source

Fierce Biotech

Relevant Date

17 September 2026


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